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VIAGRA [Sildenafil citrate] An Overview
VIAGRA [Sildenafil citrate] is the only approved and effective oral agent for the treatment of erectile dysfunction. Before that a few lines on erectile dysfunction. Erectile dysfunction [Impotence] is a condition in which erection the penis cannot be achieved during sexual intercourse/masturbation. There are many causes for erectile dysfunction. The most common cause of being increasing age. Other conditions can be: - Diabetes Mellitus - Hypertension - Heart Disease - Atherosclerosis - Lower spinal cord injury - Cancer prostate - Psychogenic - Stress Erection is achieved when there is increased blood flow to penis and hence the main organic cause is disturbance of blood flow to and from the penis. Coming back to VIAGRA [Sildenafil citrate], Viagra is a selective and potent inhibitor of cyclic guanosine monophosphate [cGMP] specific phosphodiesterase type 5 inhibitor [PDE5] which is the predominant phosphodiesterase isoform found in the penis. It is administered in doses of 25, 50 and 100 mg, and enhances erection after sexual stimulation. The onset of action is around 60-90 mins. Sildenafil (compound UK-92,480) was synthesized by a group of chemists working at Pfizer's Sandwich, Kent research facility in England. It was initially studied for use in hypertension and angina pectoris. The first clinical trials were conducted in Morriston Hospital in Swansea. Phase I clinical trials under the direction of Ian Osterloh suggested that the drug had little effect on angina, but that it could induce marked penile erections. VIAGRA [Sildenafil citrate] was approved for use in erectile dysfunction by the Food and Drug Administration on March 27, 1998, becoming the first pill approved to treat erectile dysfunction Reduced initial doses should be considered for patients, who are elderly, have renal insufficiency, or are taking medications that inhibit the CYP3A4 metabolic pathway in the liver [e.g., erythromycin, cimetidine, ketoconazole] as they may increase the serum concentration of sildenafil. The drug does not affect ejaculation, orgasm or sexual drive. When sexual stimulation causes local release of NO, inhibition of PDE5 by VIAGRA [Sildenafil citrate] causes increased levels of cGMP in the corpus cavernosum of the penis resulting in smooth muscle relaxation and inflow of blood to the corpus cavernosum. Side Effects: ?? Headaches ?? Facial flushing ?? ringing in ears, or sudden hearing loss ?? Dyspepsia ?? Nasal congestion. ?? Abnormal vision [blue halo effect] ?? Diarrhea ?? Dizziness ?? Rashes Viagra can decrease blood flow to the optic nerve of the eye, causing sudden vision loss:- Special precautions: In patients with ?? Bleeding disorders such as hemophilia ?? Liver disorder ?? Kidney disorder ?? Active peptic ulcerations and ?? Anatomical deformation of the penis, such as peyronie's disease. ?? Retinitis pigmentosa Contraindications: VIAGRA [Sildenafil citrate], is contraindicated in men receiving nitrate therapy for cardiovascular disease, including agents delivered by oral, sublingual, trans-nasal or topical routes. These agents can potentates its hypotensive effect and may result in profound shock. Viagra should be avoided in patients with congestive heart failure and cardiomyopathy because of the risk of vascular collapse.
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Learn More about
Natural Male Enhancements
CAVERTA is a tablet used to treat erectile dysfunction (impotence) in men. It can help men who have erectile dysfunction get and sustain an erection when they are sexually excited. One does not get an erection just by taking this medicine. CAVERTA helps a man with erectile dysfunction get an erection only when he is sexually excited. CAVERTA enables many men with ED to respond to sexual... 
Before we discuss the different erectile dysfunction treatments let\'s have an overview of what erectile dysfunction is. Erectile dysfunction is what others call impotence. It\'s when a man can\'t get an erection during sex or even when masturbating. You\'re also considered suffering from erectile dysfunction or ED if you can\'t keep your penis hard and erected long enough to finish having...
For many men who undergo from problems of premature ejaculation or erectile dysfunction, the problem can be one that is not easy to talk about and hard to treat. This is an embarrassment, because it doesn't have to be this way; many men suffer from erectile dysfunction, and there are many sexual treatments that you can try. If you are having problems with erectile dysfunction or you feel that...
Cheap generic Viagra has become the necessarily of life for those men who face sexual disorders like erectile dysfunction or impotency. In order to fight this problem one needs to change his attitude towards life after noticing the very first symptom of this disease. With the rising development in the field of medicines, this ailment has become very much treatable. Today, the problem of erectile...
About Viagra
Sildenafil, known to the public as Viagra, was developed by Pfizer in 1988 to help men who suffer from impotence. Erectile Dysfunction (ED), which is a medical term for impotence, is a sexual dysfunction classified when men have an inability to obtain or maintain an erection. Men who suffer from this condition are still able to ejaculate.
Viagra, an approved ED...
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